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1 Nucleoside triphosphate - Wikipedia
https://en.wikipedia.org/wiki/Nucleoside_triphosphate
A nucleoside triphosphate is a nucleotide containing a nitrogenous base bound to a 5-carbon sugar (either ribose or deoxyribose), with three phosphate ...
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2 3′-O-modified nucleotides as reversible terminators ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034218/
These nucleotide analogues are modified with a reversible chemical moiety capping the 3′-OH group to temporarily terminate the polymerase ...
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3 The Chemistry of the Addition of Substrates of DNA Replication
https://www.sparknotes.com/biology/molecular/dnareplicationandrepair/section2/
While each nucleotide added to a growing DNA chain lacks an -OH group at its 2' position, it retains its 3' -OH. This hydroxyl group is used to attack the ...
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4 Nucleotides and the double helix - Life Sciences Cyberbridge
http://cyberbridge.mcb.harvard.edu/dna_1.html
The third principle feature of a nucleotide is the base, which is attached to the 1' carbon of the ribose. Although each nucleotide in DNA contains identical ...
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5 During DNA replication, the 3' - OH of the growing DNA chain ...
https://homework.study.com/explanation/during-dna-replication-the-3-oh-of-the-growing-dna-chain-attacks-which-phosphate-of-an-incoming-nucleotide.html
During DNA replication, the 3' -OH group on the growing DNA chain attacks the first phosphate of an incoming nucleotide. Before their addition to a DNA ...
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6 Deoxyribonucleoside Triphosphate - dNTPs - ScienceDirect.com
https://www.sciencedirect.com/topics/medicine-and-dentistry/deoxyribonucleoside-triphosphate
(2) dNTP pool balance, which influences nucleotide selectivity at the insertion step; ... D The Relevance of DNA Precursor Pools to Repair.
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7 Nucleotides - Bartleby.com
https://www.bartleby.com/subject/science/biology/concepts/nucleotides
It is an organic molecule made up of three basic components- a nitrogenous base, phosphate,and pentose sugar. The nucleotides are important for metabolic ...
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8 OH unblocked reversible terminators by molecular tuning of 2 ...
https://academic.oup.com/nar/article/39/6/e39/2411723
This terminator is based on 5-hydroxymethyl-2′-deoxyuridine triphosphate (HOMedUTP), a hypermodified nucleotide found naturally in the genomes of numerous ...
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9 DNA Structure
https://www.ndsu.edu/pubweb/~mcclean/plsc731/Genome-sequencing-PMG-overheads.pdf
This group is important because in a. DNA chain it undergoes a reaction with the. 3' OH group to produce polydeoxynucleotide. The final feature of the molecule ...
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10 Polymerization of Nucleotides (Phosphodiester Bonds)
https://www2.chem.wisc.edu/deptfiles/genchem/netorial/modules/biomolecules/modules/dna1/dna13.htm
The 3' hydroxyl group forms a bond to the phosphorus atom of the free nucleotide closest to the 5' oxygen atom. Meanwhile, the bond between the first phosphorus ...
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11 The pKa's of 2'-Hydroxyl Group in Nucleosides and Nucleotides
https://pubs.acs.org/doi/10.1021/ja0036312
The 2'-OH group has major structural implications in that it is involved in recognition, processing, and catalytic properties of RNA,1c-e such ...
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12 Enzymatic Cleavage of 3'-Esterified Nucleotides Enables a ...
https://www.nature.com/articles/s41598-020-64541-z
by SW LinWu · 2020 · Cited by 2 —
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13 5. DNA Replication in Prokaryotes 5/12 - LabXchange
https://www.labxchange.org/library/items/lx-pb:8e06e316-6ab2-3fa3-a189-70461a6f2c66:html:bb60df43
DNA polymerase has two important restrictions: it is able to add nucleotides only in the 5' to 3' direction (a new DNA strand can be only ...
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14 Nucleotides, DNA, and RNA - Knowledge @ AMBOSS
https://www.amboss.com/us/knowledge/Nucleotides,_DNA,_and_RNA/
› knowledge › Nucleotides,_...
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15 5' - 3' direction - The School of Biomedical Sciences Wiki
https://teaching.ncl.ac.uk/bms/wiki/index.php/5%27_-_3%27_direction
The phosphate group attached to the 5' end of one nucleotide and the hydroxyl group at the 3' end of another nucleotide have the potential to ...
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16 Method of detecting a nucleotide change in nucleic acids
https://www.freepatentsonline.com/4988617.html
BACKGROUND OF THE INVENTION Nucleic acid analysis, particularly for DNA, is. becoming important in the diagnosis of infectious as well as ...
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17 Unraveling RNA—The importance of a 2' hydroxyl - IDT
https://www.idtdna.com/pages/education/decoded/article/unraveling-rna-the-importance-of-a-2-hydroxyl
› education › decoded › article
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18 Methods for Labeling Nucleic Acids - Thermo Fisher Scientific
https://www.thermofisher.com/us/en/home/life-science/protein-biology/protein-biology-learning-center/protein-biology-resource-library/pierce-protein-methods/methods-labeling-nucleic-acids.html
Modified nucleotides can be added to the 3′ recessed-end of RNA when hybridized to a complementary DNA oligonucleotide producing a 5′ overhang. Protein ...
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19 Addition of nucleotide on the 3′OH terminus of 21-mer PNA ...
https://www.researchgate.net/figure/Addition-of-nucleotide-on-the-3OH-terminus-of-21-mer-PNA-chimeric-primer-49-mer-DNA_fig3_241080542
› figure › Addition-of-nucle...
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20 Phosphodiester bond - Definition and Examples - Biology Online
https://www.biologyonline.com/dictionary/phosphodiester-bond
The 3′- carbon is linked with the 5′- carbon in the DNA and RNA via the phosphodiester bonds and thus they act as the backbone of nucleotides.
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21 The definition to 5' end and 3' end of a DNA strand - YouTube
https://www.youtube.com/watch?v=qWZYpHSXvJo
MrSimpleScience
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22 Why is DNA replication performed in the 5' to 3' direction?
https://biology.stackexchange.com/questions/477/why-is-dna-replication-performed-in-the-5-to-3-direction
dNTP is a nucleotide which has two additional phosphates attached to its 5' end. In order to join the 3'OH group with the phosphate of the next ...
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23 Below is an example of _ nucleotide showing the 2', 3' and 5 ...
https://www.numerade.com/ask/question/below-is-an-example-of-_-nucleotide-showing-the-2-3-and-5-carbon-positions-without-the-attached-groups-phosphate-and-oh-hydroxyl-what-combination-of-groups-at-what-position-would-dideoxynucl-71568/
VIDEO ANSWER: We'Re looking at a nucleotide and we can see some carbons, we need to know what groups we would find on the did ... SP 3'0H 3OH and 2'0H d.
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24 Biofundamentals @ UC Boulder- Nucleic Acid Structure
https://virtuallaboratory.colorado.edu/Biofundamentals-web/lectureNotes-Revision/Topic3-2_NucleicAcids.htm
The basic repeating unit of nucleic acids are known as nucleotides. A nucleotide consists of three distinct chemical groups, a 5-carbon sugar (ribose or ...
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25 DNA Damage Recognition and Repair by DNA Ligases
https://www.mskcc.org/research/ski/labs/stewart-shuman/dna-damage-recognition-and-repair-dna-ligases
Sequestration of an extrahelical nucleotide by DNA-bound ligase is reminiscent of the “base-flipping” mechanism of target site recognition and catalysis used by ...
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26 RecBCD possesses strong coupling between DNA and nucleotide ...
https://www.biorxiv.org/content/10.1101/190215v3.full
Helicases play an essential role in the repair mechanisms for DSBs in every living ... H - RecBCD, hp - hpDNA, ss - ssDNA, doh - dohDNA, 5oh - 5ohDNA, 3oh ...
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27 Which of the following enzyme creates a homonucleotide overhang ...
https://www.toppr.com/ask/en-kw/question/which-of-the-following-enzyme-creates-a-homonucleotide-overhang-at-the-3oh-end-of-the/
Which of the following enzyme creates a homonucleotide overhang at the 3′-OH end of the DNA? It can also make blunt ends sticky by adding poly AA and poly TT.
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28 Solved What is the significance of the 3'OH in DNA | Chegg.com
https://www.chegg.com/homework-help/questions-and-answers/significance-3-oh-dna-sequencing-q40997748
During polymerization of DNA incoming nucleotide becomes incorporated into growing chain by forming phosphodiester bond. This bond is formed between free 3' ...
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29 Nucleotide - National Human Genome Research Institute
https://www.genome.gov/genetics-glossary/Nucleotide
A nucleotide consists of a sugar molecule (either ribose in RNA or deoxyribose in DNA) attached to a phosphate group and a nitrogen-containing ...
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30 Why DNA replication takes place in 5' to 3' direction not 3' to 5'?
https://www.scientificreporters.com/how/dna-replicates-5-to-3-not-3-to-5.html
dNTP is the type of nucleotide that contains two additional phosphate groups attached to its 5'end. For joining the 3'OH group with the ...
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31 nucleotide | biochemistry - Britannica
https://www.britannica.com/science/nucleotide
nucleotide, any member of a class of organic compounds in which the molecular structure comprises a nitrogen-containing unit (base) linked ...
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32 average nucleotide identity Latest Research Papers | ScienceGate
https://www.sciencegate.app/keyword/118783
Find the latest published documents for average nucleotide identity, ... the major cellular fatty acids were iso-C15 : 0, iso-C17 : 0 3OH, summed feature 3 ...
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33 Chapter 5 - Nucleic Acids Flashcards by Huba Brown
https://www.brainscape.com/flashcards/chapter-5-nucleic-acids-5514083/packs/8101718
1. Nucleotides combine to form a chain or polymerize in a series of 3' to 5' phosphodiester bonds. The 5' phosphate on one unit esterifies to the 3' OH on the ...
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34 Nucleotide Definition & Meaning - Merriam-Webster
https://www.merriam-webster.com/dictionary/nucleotide
The meaning of NUCLEOTIDE is any of several compounds that consist of a ribose or deoxyribose sugar joined to a purine or pyrimidine base ...
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35 Assignment of provisionally named CDC group NO-1 strains derived ...
https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/ijsem.0.005247?fmt=rss
Clinical significance and epidemiology of NO-1, an unusual bacterium ... SNVPhyl: a single nucleotide variant phylogenomics pipeline for microbial genomic ...
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36 Nucleotide symbols - HGMD
https://www.hgmd.cf.ac.uk/docs/nuc_lett.html
Nucleotide symbol, Full Name. A, Adenine. C, Cytosine. G, Guanine. T, Thymine. U, Uracil. R, Guanine / Adenine (purine). Y, Cytosine / Thymine (pyrimidine).
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37 Introduction to nucleic acids and nucleotides (video)
https://www.khanacademy.org/science/ap-biology/gene-expression-and-regulation/dna-and-rna-structure/v/introduction-to-nucleic-acids-and-nucleotides
› dna-and-rna-structure › i...
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38 Essentials of Medical Biochemistry: With Clinical Cases
https://books.google.com/books?id=A3u1891gHfkC&pg=PA289&lpg=PA289&dq=what+is+the+significance+of+the+3oh+on+a+nucleotide&source=bl&ots=Ap2AQsHBL1&sig=ACfU3U1d4mbI4yAP_L3hss6PifZxPUAUPg&hl=en&sa=X&ved=2ahUKEwjC1JiI9b77AhUPjIkEHRLnCI4Q6AF6BQi3ARAD
DNA polymerases, the enzymes that synthesize new DNA, can only add nucleotides to a 3-OH group and therefore extend a DNA strand in the 5 to 3 direction.
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39 NUCLEOSIDES, NUCLEOTIDES, DNA, AND RNA
https://accessmedicine.mhmedical.com/content.aspx?bookid=2355§ionid=185844443
Nucleosides (bottom) are made of a nitrogenous base, usually either a purine or pyrimidine, and a five-carbon carbohydrate ribose. A nucleotide is simply a ...
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40 Lewin's GENES X - Page 327 - Google Books Result
https://books.google.com/books?id=0pM4KbFIEb0C&pg=PA327&lpg=PA327&dq=what+is+the+significance+of+the+3oh+on+a+nucleotide&source=bl&ots=56EkQiEzAE&sig=ACfU3U2qRx-8BuooKBHdsaCRkYKwbSCLMA&hl=en&sa=X&ved=2ahUKEwjC1JiI9b77AhUPjIkEHRLnCI4Q6AF6BQi4ARAD
Frameshifts occur when an extra nucleotide is inserted or omitted. ... This is particularly important for the replication of a homopolymeric stretch—for ...
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41 Genetics: Analysis of Genes and Genomes
https://books.google.com/books?id=5G9MxI9BXm0C&pg=PA361&lpg=PA361&dq=what+is+the+significance+of+the+3oh+on+a+nucleotide&source=bl&ots=eLq48d1_UP&sig=ACfU3U1Irvr__l4mma4JBUuOaP6BoDp7Zw&hl=en&sa=X&ved=2ahUKEwjC1JiI9b77AhUPjIkEHRLnCI4Q6AF6BQi7ARAD
In the final step of splicing (Figure 10.17C), the 3OH of the guanylate ... The lariat intron is rapidly degraded into individual nucleotides by nucleases.
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